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Lil Spiky

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Lil Spiky

This strange specimen is an ordinary cell, transformed by scientists into a cancer promoting monster. Using gene transfer, researcher from the University of Eastern Finland coaxed this cell into producing large quantities of a carbohydrate compound called hyaluronan. The spiky protuberances that make this cell look like a Koosh ball are actually hyaluronan factories. Hyaluronan is part of the bodys chemical toolbelt for healing, but it can also promote inflammation and cancer. New research published in the Journal of Biological Chemistry finds that high sugar concentrations in the blood promote the production of hyaluronan, which may explain why diabetics have an elevated risk of breast cancer. Researchers hope that slowing hyaluronan production could slow the spread of cancerous cells.


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